"Bioactivity and Acemannan"
Aloe is a
member of the lily family that has been used
topically and ingested for thousands of
years. The active ingredient in the aloe
plant is found in the inner leaf gel and is
considered safe and effective if processed
properly. It is a polymannan known as
Acemannan, whose structure and functional
effects in wound healing and overall health
have been very well established.¹
Authoritative
sources consider Acemannan to be the main
active ingredient in properly processed
inner leaf gel. In the early 1980s an
acetylated polymannose, Acemannan, was
identified as an active component of Aloe
Vera Gel.²
Acemannan
works in part by stimulating the macrophage,
a key component of the immune system that is
responsible for a wide range of potential
health benefits. Acemannan has shown to
accelerate wound healing.³
Improper
manufacturing processes used by many aloe
product manufacturers can produce Aloe
products with little or no Acemannan.⁴
Currently, most manufactures do not assay
for Acemannan content in their final
products. Only when the Aloe industry begins
to routinely use validated assays to ensure
the Acemannan content and therefore the
efficacy of the commercial aloe product,
will consumers consistently experience the
astonishing health benefits attributed to
fresh Aloe.
Aloe’s active
ingredient, Acemannan, is partially and
sometimes fully removed by manufacturers
during the processing phase. Many of the
preservatives added to Aloe products for
bacterial control are toxic to skin
fibroblast, thus outweighing the benefits
and preventing the consumer from receiving
the potential benefits of Acemannan.
Currently, stabilized Aloe products are
defined as products that contain enough
preservatives to control microbial growth.
Instead, a stabilized aloe product should
maintain the right amount and size of
Acemannan during the product’s shelf life.⁵
BiAloe® is
the MOST biologically active commercially
available Aloe vera made:
-
An Aloe
Vera bio-activity assay has yet to be
perfected. In the absence of such an
assay and in light of published
literature it is readily apparent that
Acemannan is the active ingredient in
Aloe Vera. Acemannan determines
biological activity in humans and other
mammals.
-
BiAloe®
has up to 10 times the Acemannan content
compared to other commercial Aloe Vera
due to farming practices, harvesting
techniques and proprietary processing
developed by Dr. Santiago Rodriguez.
-
Lorand is
the only company that currently states
its Acemannan content on every COFA.
BiAloe® averages 17% Acemannan per
batch.
-
Until the
introduction of BiAloe® commercial
producers of Aloe Vera have tried to
specialize themselves by marketing
differentiation. Some of the common
marketing techniques used are molecular
weight, specialized processing, or
unique names to brand a commodity.
-
Aloe Vera
quality and efficacy is measured by
Acemannan content. BiAloe® is the most
bio-active commercially available Aloe
Vera made.
If you would
like to learn more, go to
http://AloeVnWell.com
or, go straight to the shopping
cart to
Buy BiAloe®.
References:
1. Eric
H. Aguayo EMBA, John E. Hall DDS, Bill H. McAnalley PhD,
Shayne A. McAnally MD,David N. McCollum, Danny Sun MD,
The Science Behind Aloe: An Introduction to Aloe Vera
and Its2009; (2):9-12
2. Johnson AR, White AC, McAnally BH. Comparison of
common topical agents for wound treatment: Cytotoxicity
for human fibroblast in culture. Wounds: a compendium of
clinical research and practice. 1989; (3): 186-192.
3. Erik
H. Aguayo EMBA, John E. Hall DDS, Bill H. McAnalley PhD,
Shayne A. McAnalley MD, David N. McCollum Danny Sun MD,
The Science Behind Aloe: Identification and Isolation of
Acemannan 2009; (3): 19-21
4. Turner CE, Williamson DA, Stroud PA, Tally DJ.
Evaluation and comparison of commercially available Aloe
Vera L. products using size exclusion chromatography
with refractive index and Multi-angle laser light
scattering detection. International Immunopharmacology.
2004; 4(14)1727-1737
5. Erik
H. Aguayo EMBA, John E. Hall DDS, Bill H. McAnalley PhD,
Shayne A. McAnally MD, David N. McCollum MD, Danny Sun
MD, The Science Behind Aloe: Properly Processing and
Manufacturing Aloe Products; 2009; (4): 25‐27
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